人 ITGA3 (NM_005501) cDNA克隆

Accession: NM_005501
基因名称: ITGA3
基因别名: VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
基因描述: Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b, mRNA.
种属: Human
CDS区长度: 3201 (查看编码区序列)
翻译后氨基酸长度: 1066 (查看氨基酸序列)
Transcript Variant: This variant (b) is missing the penultimate exon found in transcript variant a. This results in a frame-shift and a longer isoform (b) with a distinct C-terminus compared to isoform a.
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G150912 人 ITGA3 (NM_005501) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]