人 KCNK2 (NM_001017424) cDNA克隆

Accession: NM_001017424
基因名称: KCNK2
基因别名: TREK; TPKC1; TREK1; K2p2.1; TREK-1; hTREK-1c; hTREK-1e
基因描述: Homo sapiens potassium channel, subfamily K, member 2 (KCNK2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1269 (查看编码区序列)
翻译后氨基酸长度: 422 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (a).
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G151065 人 KCNK2 (NM_001017424) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]