人 LCN1 (NM_001252619) cDNA克隆

Accession: NM_001252619
基因名称: LCN1
基因别名: TP; TLC; PMFA; VEGP
基因描述: Homo sapiens lipocalin 1 (LCN1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 693 (查看编码区序列)
翻译后氨基酸长度: 230 (查看氨基酸序列)
Transcript Variant: This variant (4) uses an alternate splice site in the 3' coding region, which results in a translational frameshift, compared to variant 1. The encoded isoform (3) is longer and has a distinct C-terminus, compared to isoform 1.
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G151854 人 LCN1 (NM_001252619) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]