人 LLGL2 (NM_004524) cDNA克隆

基本信息

Accession: NM_004524
基因名称: LLGL2
基因别名: HGL; LGL2
基因描述: Homo sapiens lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3048 (查看编码区序列)
翻译后氨基酸长度: 1015 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an alternate exon in the coding region compared to variant 3, that causes a frameshift. The resulting isoform (a) is shorter and has a distinct C-terminus compared to isoform c.

订购信息

产品编号 产品名称 载体 规格 价格
G151899 人 LLGL2 (NM_004524) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LLGL2 (NM_004524) cDNA克隆 transcript variant 1
人 LLGL2 (NM_001015002) cDNA克隆 transcript variant 2
人 LLGL2 (NM_001031803) cDNA克隆 transcript variant 3

基因简介

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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