人 LNPEP (NM_175920) cDNA克隆

Accession: NM_175920
基因名称: LNPEP
基因别名: CAP; IRAP; PLAP; P-LAP
基因描述: Homo sapiens leucyl/cystinyl aminopeptidase (LNPEP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3036 (查看编码区序列)
翻译后氨基酸长度: 1011 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' exon, which results in a distinct 5' UTR and use of a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus when compared to isoform 1.
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G151992 人 LNPEP (NM_175920) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]