人 MFNG (NM_001166343) cDNA克隆

基本信息

Accession: NM_001166343
基因名称: MFNG
基因描述: Homo sapiens MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), transcript variant 2, mRNA.
种属: Human
CDS区长度: 924 (查看编码区序列)
翻译后氨基酸长度: 307 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 5' exon and lacks an alternate 5' coding exon, compared to variant 1, resulting in a protein that maintains the reading frame but is shorter, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G152398 人 MFNG (NM_001166343) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MFNG (NM_002405) cDNA克隆 transcript variant 1
人 MFNG (NM_001166343) cDNA克隆 transcript variant 2

基因简介

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009]

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