人 MLLT4 (NM_001207008) cDNA克隆

基本信息

Accession: NM_001207008
基因名称: MLLT4
基因别名: AF6; RP3-431P23.3
基因描述: Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (MLLT4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 5232 (查看编码区序列)
翻译后氨基酸长度: 1743 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1, also known as AF6i3). This isoform, which contains a C-terminal F-actin-binding site, has been shown to be involved in the regulation of epithelial wound closure and intercellular adhesion (PMID:16882694).

订购信息

产品编号 产品名称 载体 规格 价格
G152425 人 MLLT4 (NM_001207008) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MLLT4 (NM_001207008) cDNA克隆 transcript variant 1
人 MLLT4 (NM_001040000) cDNA克隆 transcript variant 2

基因简介

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]

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