人 NEFM (NM_005382) cDNA克隆

Accession: NM_005382
基因名称: NEFM
基因别名: NFM; NEF3; NF-M
基因描述: Homo sapiens neurofilament, medium polypeptide (NEFM), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2751 (查看编码区序列)
翻译后氨基酸长度: 916 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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G152913 人 NEFM (NM_005382) cDNA克隆 pDONR223 2ug质粒 点击询价

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]