人 NFATC4 (NM_001198967) cDNA克隆

Accession: NM_001198967
基因名称: NFATC4
基因别名: NFAT3; NF-ATc4
基因描述: Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (NFATC4), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2574 (查看编码区序列)
翻译后氨基酸长度: 857 (查看氨基酸序列)
Transcript Variant: This variant (5) is alternatively spliced at the 3' end compared to transcript variant 1. This results in translation termination at a downstream stop codon, and a shorter isoform (5) with a distinct C-terminus compared to isoform 1.
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G152946 人 NFATC4 (NM_001198967) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Oct 2008]