人 ANAPC7 (NM_001137664) cDNA克隆

Accession: NM_001137664
基因名称: ANAPC7
基因别名: APC7
基因描述: Homo sapiens anaphase promoting complex subunit 7 (ANAPC7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1614 (查看编码区序列)
翻译后氨基酸长度: 537 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 3' UTR and 3' coding region (compared to variant 1), which results in a frameshift. It encodes isoform b which has a shorter and distinct C-terminus compared to isoform a.
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G153973 人 ANAPC7 (NM_001137664) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]