人 SERPINF2 (NM_001165921) cDNA克隆

基本信息

Accession: NM_001165921
基因名称: SERPINF2
基因别名: AAP; API; PLI; A2AP; ALPHA-2-PI
基因描述: Homo sapiens serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site and lacks an alternate exon in the 5' coding region, compared to variant 1. The resulting isoform (b) lacks an internal segment, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G154440 人 SERPINF2 (NM_001165921) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SERPINF2 (NM_000934) cDNA克隆 transcript variant 1
人 SERPINF2 (NM_001165920) cDNA克隆 transcript variant 2
人 SERPINF2 (NM_001165921) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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