人 PRRX1 (NM_006902) cDNA克隆

Accession: NM_006902
基因名称: PRRX1
基因别名: PMX1; PRX1; AGOTC; PHOX1; PRX-1
基因描述: Homo sapiens paired related homeobox 1 (PRRX1), transcript variant pmx-1a, mRNA.
种属: Human
CDS区长度: 654 (查看编码区序列)
翻译后氨基酸长度: 217 (查看氨基酸序列)
Transcript Variant: This variant (pmx-1a) includes an alternate exon in the 3' coding region, compared to variant pmx-1b. The resulting protein (pmx-1a) has a distinct C-terminus, compared to isoform pmx-1b.
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G154568 人 PRRX1 (NM_006902) cDNA克隆 pDONR223 2ug质粒 点击询价
人 PRRX1 (NM_006902) cDNA克隆 transcript variant pmx-1a
人 PRRX1 (NM_022716) cDNA克隆 transcript variant pmx-1b

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]