The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]
人 KCNK10 (NM_021161) cDNA克隆
| Accession: | NM_021161 |
|---|---|
| 基因名称: | KCNK10 |
| 基因别名: | TREK2; TREK-2; K2p10.1 |
| 基因描述: | Homo sapiens potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1617 (查看编码区序列) |
| 翻译后氨基酸长度: | 538 (查看氨基酸序列) |
| Transcript Variant: | This variant (1, also known as TREK2 splice variant a) encodes the shortest isoform (1). |
| 人 KCNK10 (NM_021161) cDNA克隆 | transcript variant 1 |
| 人 KCNK10 (NM_138317) cDNA克隆 | transcript variant 2 |
| 人 KCNK10 (NM_138318) cDNA克隆 | transcript variant 3 |
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