人 ENOSF1 (NM_017512) cDNA克隆

Accession: NM_017512
基因名称: ENOSF1
基因别名: RTS; TYMSAS; HSRTSBETA
基因描述: Homo sapiens enolase superfamily member 1 (ENOSF1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1332 (查看编码区序列)
翻译后氨基酸长度: 443 (查看氨基酸序列)
Transcript Variant: This variant (1), also known as rTSbeta, includes an alternate coding exon and represents an alternate 3'UTR extension compared to variant 2. Translation is predicted to initiate in the second exon resulting in a distinct N-terminus.
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G155327 人 ENOSF1 (NM_017512) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins. [provided by RefSeq, Mar 2010]