Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008]
| Accession: | NM_001171083 |
|---|---|
| 基因名称: | SMPD4 |
| 基因别名: | NET13; NSMASE3; NSMASE-3 |
| 基因描述: | Homo sapiens sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) (SMPD4), transcript variant 3, mRNA. |
| 种属: | Human |
| CDS区长度: | 2295 (查看编码区序列) |
| 翻译后氨基酸长度: | 764 (查看氨基酸序列) |
| Transcript Variant: | This variant (3) lacks two alternate exons resulting in the loss of an in-frame segment in the 5' coding region, and it also lacks an alternate in-frame exon in the central coding region, compared to variant 2. The resulting isoform (3) is shorter than isoform 2. |
| 人 SMPD4 (NM_017751) cDNA克隆 | transcript variant 1 |
| 人 SMPD4 (NM_017951) cDNA克隆 | transcript variant 2 |
| 人 SMPD4 (NM_001171083) cDNA克隆 | transcript variant 3 |
Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008]