人 CDK5RAP2 (NM_018249) cDNA克隆

Accession: NM_018249
基因名称: CDK5RAP2
基因别名: C48; MCPH3; Cep215
基因描述: Homo sapiens CDK5 regulatory subunit associated protein 2 (CDK5RAP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 5682 (查看编码区序列)
翻译后氨基酸长度: 1893 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (a).
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G155430 人 CDK5RAP2 (NM_018249) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]