人 SPPL2B (NM_152988) cDNA克隆

基本信息

Accession: NM_152988
基因名称: SPPL2B
基因别名: IMP4; PSH4; PSL1; IMP-4
基因描述: Homo sapiens signal peptide peptidase like 2B (SPPL2B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1779 (查看编码区序列)
翻译后氨基酸长度: 592 (查看氨基酸序列)
Transcript Variant: This variant (2) represents the shorter transcript but encodes the longer isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G156244 人 SPPL2B (NM_152988) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SPPL2B (NM_152988) cDNA克隆 transcript variant 2
人 SPPL2B (NM_001077238) cDNA克隆 transcript variant 3
人 SPPL2B (NM_020172) cDNA克隆 transcript variant 1

基因简介

This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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