人 AHRR (NM_001242412) cDNA克隆

基本信息

Accession: NM_001242412
基因名称: AHRR
基因别名: AHH; AHHR; bHLHe77
基因描述: Homo sapiens aryl-hydrocarbon receptor repressor (AHRR), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2106 (查看编码区序列)
翻译后氨基酸长度: 701 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as AHRRdelta8) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2) missing an 18 aa internal protein segment compared to isoform 1. PMID:19380484 reports that this isoform is the predominant form expressed in human tissues and cell lines, and is more active than the longer isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G156521 人 AHRR (NM_001242412) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AHRR (NM_020731) cDNA克隆 transcript variant 1
人 AHRR (NM_001242412) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

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