This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]
人 RHOU (NM_021205) cDNA克隆
| Accession: | NM_021205 |
|---|---|
| 基因名称: | RHOU |
| 基因别名: | ARHU; WRCH1; hG28K; CDC42L1; DJ646B12.2; fJ646B12.2 |
| 基因描述: | Homo sapiens ras homolog family member U (RHOU), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 777 (查看编码区序列) |
| 翻译后氨基酸长度: | 258 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the longer transcript and encodes the functional protein. |
| 人 RHOU (NM_021205) cDNA克隆 | transcript variant 1 |
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