小鼠 Ghrl (NM_001286405) cDNA克隆

基本信息

Accession: NM_001286405
基因名称: Ghrl
基因别名: Ghr; m46; MTLRP; MTLRPAP; 2210006E23Rik
基因描述: Mus musculus ghrelin (Ghrl), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 261 (查看编码区序列)
翻译后氨基酸长度: 86 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the 3' coding region resulting in a frameshift compared to variant 1. The encoded protein (isoform 3) is shorter than isoform 1 and has a distinct C-terminus. Proteolytic cleavage to produce ghrelin and a C-terminal peptide may occur but has yet to be demonstrated conclusively (PMID 15471962). This isoform lacks the obestatin ligand.

订购信息

产品编号 产品名称 载体 规格 价格
G156923 小鼠 Ghrl (NM_001286405) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Ghrl (NM_021488) cDNA克隆 transcript variant 1
小鼠 Ghrl (NM_001286404) cDNA克隆 transcript variant 2
小鼠 Ghrl (NM_001286405) cDNA克隆 transcript variant 3
小鼠 Ghrl (NM_001286406) cDNA克隆 transcript variant 4

基因简介

This gene encodes a preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. The hormone ghrelin plays a role in enhancing appetite and has numerous other biological functions that include stimulating the secretion of growth hormone (somatotropin) from the anterior pituitary gland. Obestatin is thought to be a hormone that functions in decreasing appetite. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]

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