人 CXCL12 (NM_001178134) cDNA克隆

Accession: NM_001178134
基因名称: CXCL12
基因别名: IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12
基因描述: Homo sapiens chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 4, mRNA.
种属: Human
CDS区长度: 423 (查看编码区序列)
翻译后氨基酸长度: 140 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate segment, which results in a frameshift, compared to variant 1. The resulting protein (isoform delta) is longer and has a distinct C-terminus compared to isoform alpha.
产品编号 产品名称 载体 规格 价格
G157602 人 CXCL12 (NM_001178134) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]