The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
人 CRLF2 (NM_001012288) cDNA克隆
| Accession: | NM_001012288 |
|---|---|
| 基因名称: | CRLF2 |
| 基因别名: | CRL2; TSLPR; CRLF2Y |
| 基因描述: | Homo sapiens cytokine receptor-like factor 2 (CRLF2), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 780 (查看编码区序列) |
| 翻译后氨基酸长度: | 259 (查看氨基酸序列) |
| 人 CRLF2 (NM_022148) cDNA克隆 | transcript variant 1 |
| 人 CRLF2 (NM_001012288) cDNA克隆 | transcript variant 2 |
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