人 SH3BP2 (NM_003023) cDNA克隆

基本信息

Accession: NM_003023
基因名称: SH3BP2
基因别名: 3BP2; CRBM; CRPM; 3BP-2; RES4-23
基因描述: Homo sapiens SH3-domain binding protein 2 (SH3BP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1686 (查看编码区序列)
翻译后氨基酸长度: 561 (查看氨基酸序列)
Transcript Variant: This variant (1) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G158005 人 SH3BP2 (NM_003023) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SH3BP2 (NM_003023) cDNA克隆 transcript variant 1
人 SH3BP2 (NM_001122681) cDNA克隆 transcript variant 2
人 SH3BP2 (NM_001145856) cDNA克隆 transcript variant 3
人 SH3BP2 (NM_001145855) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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