人 SIPA1 (NM_153253) cDNA克隆

Accession: NM_153253
基因名称: SIPA1
基因别名: SPA1
基因描述: Homo sapiens signal-induced proliferation-associated 1 (SIPA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3129 (查看编码区序列)
翻译后氨基酸长度: 1042 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform.
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G158208 人 SIPA1 (NM_153253) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]