人 SLC5A1 (NM_001256314) cDNA克隆

基本信息

Accession: NM_001256314
基因名称: SLC5A1
基因别名: NAGT; SGLT1; D22S675
基因描述: Homo sapiens solute carrier family 5 (sodium/glucose cotransporter), member 1 (SLC5A1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1614 (查看编码区序列)
翻译后氨基酸长度: 537 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks several 5' exons compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a weak Kozak sequence and a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G158342 人 SLC5A1 (NM_001256314) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLC5A1 (NM_000343) cDNA克隆 transcript variant 1
人 SLC5A1 (NM_001256314) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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