人 XAGE1B (NM_001097594) cDNA克隆

基本信息

Accession: NM_001097594
基因名称: XAGE1B
基因别名: CTP9; CT12.1; GAGED2; XAGE-1; CT12.1B
基因描述: Homo sapiens X antigen family, member 1B (XAGE1B), transcript variant a, mRNA.
种属: Human
CDS区长度: 246 (查看编码区序列)
翻译后氨基酸长度: 81 (查看氨基酸序列)
Transcript Variant: This variant (a, also known as XAGE-1a) encodes the longer isoform (a, also known as isoform XAGE-1b). This variant also includes a major downstream transcription start site, which results in the variant referred to as XAGE-1b in the literature. Both XAGE-1a and XAGE-1b encode the same isoform. This RefSeq contains an in-frame start site 65 codons upstream from the currently annotated site but is not being annotated as a start site since it is in a weak Kozak sequence context and experimental evidence indicates that the downstream AUG is used. (PMID: 12479262 and PMID: 17335148)

订购信息

产品编号 产品名称 载体 规格 价格
G158403 人 XAGE1B (NM_001097594) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 XAGE1B (NM_001097594) cDNA克隆 transcript variant a
人 XAGE1B (NM_001097596) cDNA克隆 transcript variant d

基因简介

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]

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