人 SFTPA1 (NM_005411) cDNA克隆

Accession: NM_005411
基因名称: SFTPA1
基因别名: SPA; PSAP; PSPA; SP-A; SPA1; PSP-A; SFTP1; SP-A1; COLEC4; SFTPA1B
基因描述: Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 747 (查看编码区序列)
翻译后氨基酸长度: 248 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 3 and 4 encode the same isoform (1).
产品编号 产品名称 载体 规格 价格
G158424 人 SFTPA1 (NM_005411) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]