人 AURKC (NM_003160) cDNA克隆

基本信息

Accession: NM_003160
基因名称: AURKC
基因别名: AIE2; AIK3; ARK3; AurC; SPGF5; STK13; aurora-C
基因描述: Homo sapiens aurora kinase C (AURKC), transcript variant 3, mRNA.
种属: Human
CDS区长度: 828 (查看编码区序列)
翻译后氨基酸长度: 275 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site at the 5' end of the first intron and an alternate downstream translation initiation site, compared to variant 1. The encoded protein (isoform 3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G160380 人 AURKC (NM_003160) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AURKC (NM_001015878) cDNA克隆 transcript variant 1
人 AURKC (NM_001015879) cDNA克隆 transcript variant 2
人 AURKC (NM_003160) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

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