This gene encodes a secreted protein that is a core component of the complement 8 (C8) complex. C8 is part of the membrane attack complex which participates in the innate immune response against bacterial pathogens. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
小鼠 C8g (NM_001271777) cDNA克隆
| Accession: | NM_001271777 |
|---|---|
| 基因名称: | C8g |
| 基因描述: | Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 2, mRNA. |
| 种属: | Mouse |
| CDS区长度: | 507 (查看编码区序列) |
| 翻译后氨基酸长度: | 168 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1. |
| 小鼠 C8g (NM_027062) cDNA克隆 | transcript variant 1 |
| 小鼠 C8g (NM_001271777) cDNA克隆 | transcript variant 2 |
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