人 TFE3 (NM_006521) cDNA克隆

基本信息

Accession: NM_006521
基因名称: TFE3
基因别名: TFEA; RCCP2; RCCX1; bHLHe33
基因描述: Homo sapiens transcription factor binding to IGHM enhancer 3 (TFE3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1728 (查看编码区序列)
翻译后氨基酸长度: 575 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G161840 人 TFE3 (NM_006521) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TFE3 (NM_006521) cDNA克隆 transcript variant 1
人 TFE3 (NM_001282142) cDNA克隆 transcript variant 2

基因简介

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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