人 TPBG (NM_006670) cDNA克隆

Accession: NM_006670
基因名称: TPBG
基因别名: 5T4; M6P1; 5T4AG
基因描述: Homo sapiens trophoblast glycoprotein (TPBG), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1263 (查看编码区序列)
翻译后氨基酸长度: 420 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
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G162336 人 TPBG (NM_006670) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]