人 TPM2 (NM_213674) cDNA克隆

Accession: NM_213674
基因名称: TPM2
基因别名: DA1; DA2B; NEM4; TMSB; AMCD1
基因描述: Homo sapiens tropomyosin 2 (beta) (TPM2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 855 (查看编码区序列)
翻译后氨基酸长度: 284 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate internal exon and an alternate 3' exon, as compared to variant 1. The resulting isoform (2) has a different internal segment and a different C-terminus, but has the same protein size, as compared to isoform 1.
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G162362 人 TPM2 (NM_213674) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]