人 YWHAZ (NM_003406) cDNA克隆

Accession: NM_003406
基因名称: YWHAZ
基因别名: YWHAD; KCIP-1; 14-3-3-zeta
基因描述: Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta (YWHAZ), transcript variant 1, mRNA.
种属: Human
CDS区长度: 738 (查看编码区序列)
翻译后氨基酸长度: 245 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. All six transcripts encode the same protein.
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G164139 人 YWHAZ (NM_003406) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]