人 CACNA1B (NM_001243812) cDNA克隆

Accession: NM_001243812
基因名称: CACNA1B
基因别名: BIII; CACNN; Cav2.2; CACNL1A5
基因描述: Homo sapiens calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 6714 (查看编码区序列)
翻译后氨基酸长度: 2237 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
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G164850 人 CACNA1B (NM_001243812) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]