SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]
人 SIKE1 (NM_001102396) cDNA克隆
| Accession: | NM_001102396 |
|---|---|
| 基因名称: | SIKE1 |
| 基因别名: | SIKE; RP5-1000E10.4 |
| 基因描述: | Homo sapiens suppressor of IKBKE 1 (SIKE1), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 636 (查看编码区序列) |
| 翻译后氨基酸长度: | 211 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) encodes the longer isoform (1). |
| 人 SIKE1 (NM_001102396) cDNA克隆 | transcript variant 1 |
| 人 SIKE1 (NM_025073) cDNA克隆 | transcript variant 2 |
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