人 HMGA2 (NM_003484) cDNA克隆

基本信息

Accession: NM_003484
基因名称: HMGA2
基因别名: BABL; LIPO; HMGIC; HMGI-C; STQTL9
基因描述: Homo sapiens high mobility group AT-hook 2 (HMGA2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 321 (查看编码区序列)
翻译后氨基酸长度: 106 (查看氨基酸序列)
Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, including an alternate exon which results in an early stop codon. The resulting protein (isoform b) has a distinct C-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G165828 人 HMGA2 (NM_003484) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 HMGA2 (NM_003483) cDNA克隆 transcript variant 1
人 HMGA2 (NM_003484) cDNA克隆 transcript variant 2

基因简介

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

相关产品