人 ARID5B (NM_001244638) cDNA克隆

Accession: NM_001244638
基因名称: ARID5B
基因别名: MRF2; DESRT; MRF-2
基因描述: Homo sapiens AT rich interactive domain 5B (MRF1-like) (ARID5B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2838 (查看编码区序列)
翻译后氨基酸长度: 945 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
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G166463 人 ARID5B (NM_001244638) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]