人 POLR1B (NM_001282774) cDNA克隆

基本信息

Accession: NM_001282774
基因名称: POLR1B
基因别名: RPA2; RPA135; Rpo1-2
基因描述: Homo sapiens polymerase (RNA) I polypeptide B, 128kDa (POLR1B), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2859 (查看编码区序列)
翻译后氨基酸长度: 952 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks two alternate exons that result in a short frameshift in the central coding region, and also uses an alternate splice site that restores the reading frame in the remaining coding region, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G166471 人 POLR1B (NM_001282774) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 POLR1B (NM_019014) cDNA克隆 transcript variant 1
人 POLR1B (NM_001137604) cDNA克隆 transcript variant 2
人 POLR1B (NM_001282772) cDNA克隆 transcript variant 3
人 POLR1B (NM_001282774) cDNA克隆 transcript variant 4
人 POLR1B (NM_001282776) cDNA克隆 transcript variant 5
人 POLR1B (NM_001282777) cDNA克隆 transcript variant 6
人 POLR1B (NM_001282779) cDNA克隆 transcript variant 7

基因简介

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

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