人 LTBP4 (NM_003573) cDNA克隆

基本信息

Accession: NM_003573
基因名称: LTBP4
基因别名: ARCL1C; LTBP-4; LTBP4L; LTBP4S
基因描述: Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4764 (查看编码区序列)
翻译后氨基酸长度: 1587 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G166499 人 LTBP4 (NM_003573) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LTBP4 (NM_001042544) cDNA克隆 transcript variant 1
人 LTBP4 (NM_003573) cDNA克隆 transcript variant 2
人 LTBP4 (NM_001042545) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

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