人 NSMAF (NM_001144772) cDNA克隆

Accession: NM_001144772
基因名称: NSMAF
基因别名: FAN
基因描述: Homo sapiens neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2847 (查看编码区序列)
翻译后氨基酸长度: 948 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR and coding region. Isoform 2 has a longer N-terminus, compared to isoform 1.
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G166541 人 NSMAF (NM_001144772) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]