人 GEMIN2 (NM_001009182) cDNA克隆

基本信息

Accession: NM_001009182
基因名称: GEMIN2
基因别名: SIP1; SIP1-delta
基因描述: Homo sapiens gem (nuclear organelle) associated protein 2 (GEMIN2), transcript variant beta, mRNA.
种属: Human
CDS区长度: 798 (查看编码区序列)
翻译后氨基酸长度: 265 (查看氨基酸序列)
Transcript Variant: This variant (beta) lacks an in-frame exon, compared to variant alpha. It encodes isoform beta which is shorter than isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G166691 人 GEMIN2 (NM_001009182) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GEMIN2 (NM_003616) cDNA克隆 transcript variant alpha
人 GEMIN2 (NM_001009182) cDNA克隆 transcript variant beta
人 GEMIN2 (NM_001009183) cDNA克隆 transcript variant gamma

基因简介

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]

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