人 PPFIBP1 (NM_003622) cDNA克隆

基本信息

Accession: NM_003622
基因名称: PPFIBP1
基因别名: L2; SGT2; hSGT2; hSgt2p
基因描述: Homo sapiens PTPRF interacting protein, binding protein 1 (liprin beta 1) (PPFIBP1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3018 (查看编码区序列)
翻译后氨基酸长度: 1005 (查看氨基酸序列)
Transcript Variant: This variant (1) has multiple differences in the coding sequence compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is 6 aa shorter compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G166730 人 PPFIBP1 (NM_003622) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PPFIBP1 (NM_003622) cDNA克隆 transcript variant 1
人 PPFIBP1 (NM_177444) cDNA克隆 transcript variant 2
人 PPFIBP1 (NM_001198915) cDNA克隆 transcript variant 3
人 PPFIBP1 (NM_001198916) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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