人 CCNB3 (NM_033670) cDNA克隆

Accession: NM_033670
基因名称: CCNB3
基因描述: Homo sapiens cyclin B3 (CCNB3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 876 (查看编码区序列)
翻译后氨基酸长度: 291 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks four consecutive in-frame coding exons compared to variant 3. This results in a shorter isoform (1) missing a 1104 aa internal protein segment compared to isoform 3.
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G166822 人 CCNB3 (NM_033670) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]