人 CDC14B (NM_033331) cDNA克隆

Accession: NM_033331
基因名称: CDC14B
基因别名: CDC14B3; Cdc14B1; Cdc14B2; hCDC14B
基因描述: Homo sapiens cell division cycle 14B (CDC14B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1497 (查看编码区序列)
翻译后氨基酸长度: 498 (查看氨基酸序列)
Transcript Variant: This variant (2) encodes the longest isoform (2).
产品编号 产品名称 载体 规格 价格
G166869 人 CDC14B (NM_033331) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]