人 REPS2 (NM_001080975) cDNA克隆

Accession: NM_001080975
基因名称: REPS2
基因别名: POB1
基因描述: Homo sapiens RALBP1 associated Eps domain containing 2 (REPS2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1980 (查看编码区序列)
翻译后氨基酸长度: 659 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a protein (isoform 2) that is one aa shorter than isoform 1.
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G167255 人 REPS2 (NM_001080975) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]