人 CD8A (NM_171827) cDNA克隆

基本信息

Accession: NM_171827
基因名称: CD8A
基因别名: CD8; MAL; p32; Leu2
基因描述: Homo sapiens CD8a molecule (CD8A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 597 (查看编码区序列)
翻译后氨基酸长度: 198 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform 2) lacks an internal segment including the transmembrane domain compared to isoform 1, resulting in a secreted protein.

订购信息

产品编号 产品名称 载体 规格 价格
G167300 人 CD8A (NM_171827) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CD8A (NM_001768) cDNA克隆 transcript variant 1
人 CD8A (NM_171827) cDNA克隆 transcript variant 2
人 CD8A (NM_001145873) cDNA克隆 transcript variant 3

基因简介

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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