人 CACNA2D2 (NM_001005505) cDNA克隆

Accession: NM_001005505
基因名称: CACNA2D2
基因别名: CACNA2D; LUAC11.1
基因描述: Homo sapiens calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3438 (查看编码区序列)
翻译后氨基酸长度: 1145 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The resulting isoform (a) differs at two internal segments, compared to isoform c.
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G167301 人 CACNA2D2 (NM_001005505) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]