人 CDC25B (NM_021872) cDNA克隆

基本信息

Accession: NM_021872
基因名称: CDC25B
基因描述: Homo sapiens cell division cycle 25B (CDC25B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1620 (查看编码区序列)
翻译后氨基酸长度: 539 (查看氨基酸序列)
Transcript Variant: This variant (3), also known as CDC25B2, lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 3) compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G168083 人 CDC25B (NM_021872) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CDC25B (NM_021873) cDNA克隆 transcript variant 1
人 CDC25B (NM_001287524) cDNA克隆 transcript variant 10
人 CDC25B (NM_004358) cDNA克隆 transcript variant 2
人 CDC25B (NM_021872) cDNA克隆 transcript variant 3
人 CDC25B (NM_001287516) cDNA克隆 transcript variant 4
人 CDC25B (NM_001287517) cDNA克隆 transcript variant 5
人 CDC25B (NM_001287518) cDNA克隆 transcript variant 6
人 CDC25B (NM_001287519) cDNA克隆 transcript variant 7
人 CDC25B (NM_001287520) cDNA克隆 transcript variant 8
人 CDC25B (NM_001287522) cDNA克隆 transcript variant 9

基因简介

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

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