人 SALL3 (NM_171999) cDNA克隆

Accession: NM_171999
基因名称: SALL3
基因别名: ZNF796
基因描述: Homo sapiens spalt-like transcription factor 3 (SALL3), mRNA.
种属: Human
CDS区长度: 3903 (查看编码区序列)
翻译后氨基酸长度: 1300 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G169394 人 SALL3 (NM_171999) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011]