人 GRIN1 (NM_001185091) cDNA克隆

基本信息

Accession: NM_001185091
基因名称: GRIN1
基因别名: NR1; MRD8; GluN1; NMDA1; NMDAR1
基因描述: Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2721 (查看编码区序列)
翻译后氨基酸长度: 906 (查看氨基酸序列)
Transcript Variant: This variant (5) contains an alternate coding segment, lacks a different alternate coding segment, and uses a different splice site in the 3' coding region, compared to variant NR1-3. The resulting protein (isoform 5) is shorter and has a distinct C-terminus when it is compared to isoform NR1-3. This variant has also been named isoform 3b or NMDAR1-3b.

订购信息

产品编号 产品名称 载体 规格 价格
G169456 人 GRIN1 (NM_001185091) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GRIN1 (NM_001185091) cDNA克隆 transcript variant 5
人 GRIN1 (NM_000832) cDNA克隆 transcript variant NR1-1
人 GRIN1 (NM_021569) cDNA克隆 transcript variant NR1-2
人 GRIN1 (NM_007327) cDNA克隆 transcript variant NR1-3
人 GRIN1 (NM_001185090) cDNA克隆 transcript variant NR1-4

基因简介

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

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